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. 2022 May 22;14(10):2552. doi: 10.3390/cancers14102552

Table 2.

Baseline characteristics and comparison stratified by MCT4 score.

Variables MCT4 Score
0, n = 46
MCT4 Score
1, n = 32
MCT4 Score
2, n = 26
P between Groups
Sex
Male, n (%) 28 (60.9) 14 (43.8) 14 (53.8) 0.329
Age, median (IQR) years 62 (56–72) 69 (56–75) 65 (47–70) 0.258
T-Class 0.713
T1–2, n (%) 11 (23.9) 7 (21.9) 9 (34.6)
T3, n (%) 19 (41.3) 16 (50.0) 9 (34.6)
T4, n (%) 16 (34.8) 9 (28.1) 8 (30.8)
N-Class 0.308
N0, n (%) 10 (21.7) 6 (18.8) 2 (7.7)
N1–2, n (%) 36 (78.3) 26 (81.3) 24 (92.3)
M-Class 0.948
M0, n (%) 29 (63.0) 19 (59.4) 16 (61.5)
M1, n (%) 17 (37.0) 13 (40.6) 10 (38.5)
Stage 0.959
I–II, n (%) 6 (13.0) 3 (9.4) 2 (7.7)
III, n (%) 23 (50.0) 16 (50.0) 14 (53.8)
IV, n (%) 17 (37.0) 13 (40.6) 10 (38.5)
Grade
1, n (%) 35 (76.1) 27 (84.4) 18 (69.2) 0.389
2, n (%) 11 (23.9) 5 (15.6) 8 (30.8)
Tumor location 0.203
Ileum, n (%) 42 (91.3) 32 (100) 25 (96.2)
Jejunum, n (%) 4 (8.7) 0 1 (3.8)
Somatostatin analogue treatment
Yes, n (%) 24 (52.2) 20 (62.5) 16 (61.5) 0.596
Chemotherapy 0.669
No, n (%) 35 (76.1) 27 (84.4) 24 (92.3)
Preoperative, n (%) 3 (6.5) 1 (3.1) 0
Postoperative, n (%) 6 (13.0) 3 (9.4) 2 (7.7)
Multiple primary tumors
Yes, n (%) 15 (33.3) 1 (35.5) 4 (15.4) 0.187
P-CgA
≥3 nmol/L, n (%) 34 (91.9) 25 (86.2) 21 (84.0) 0.609
Median (IQR) nmol/L 7.6 (4.1–39.5) 5.0 (3.4–10.2) 5.5 (3.3–12.0) 0.209
dU-5-HIAA
≥42 µmol/L, n (%) 19 (59.4) 15 (55.6) 15 (68.2) 0.658
Median (IQR) µmol/L 74 (32–266) 44 (24–104) 58 (27–222) 0.258

P-CgA, plasma chromogranin A; dU-5-HIAA, 24 h urine hydroxyindoleacetic acid.