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. 2022 May 17;14(10):2462. doi: 10.3390/cancers14102462

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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The fluorescence intensity analysis of SULF1-800CW and SPARC-800CW on EMR specimens. (a) The quantified intrinsic fluorescence with MDSFR/SFF spectroscopy of SULF1-800CW (left) and SPARC-800CW (right) before tracer spraying (pre-tracer), after tracer spraying, and before rinsing (post-tracer) and after rinsing (post-rinse). (b) The mean fluorescence intensity (MFI) of SULF1-800CW (left) and SPARC-800CW (right) before tracer spraying (pre-tracer), after tracer spraying before rinsing (post-tracer), after rinsing (post-rinse). (c) The MFI of dysplastic BE (DBE) tissue compared to non-dysplastic (ND) tissue. Each line connects paired data from the same specimen. DBE: dysplastic Barrett’s esophagus; EMR: endoscopic mucosal resection; MFI: mean fluorescence intensity; NDBE: non-dysplastic Barrett’s esophagus.