Table 2.

Median (interquartile range) metal concentrations (μg/kg) in aerosols by flavor.

	Median (IQR) in CD			Overall p-value	Linear regression p-value			Beta value (95% CI)
	Fruit (n=10)	Tobacco (n=17)	Menthol (n=19)		Fruit vs. Tobacc	Fruit vs. Menthol	Tobacco vs. Menthol	Fruit vs. Tobacco	Fruit vs. Menthol	Tobacco vs. Menthol
Al	6.02 (4.29–8.65)	16.3 (12.3–35.6)	9.96 (6.56–16.0)	0.10	0.03	0.12	0.44	0.82 (0.07, 1.57)	0.57 (−0.16, 1.31)	−0.25 (−0.87, 0.38)
As	0.09 (0.09–0.12)	0.13 (0.10–0.36)	0.09 (0.09–0.10)	0.03	0.13	0.41	0.008	0.56 (−0.18, 1.30)	−0.30 (−1.03, 0.43)	−0.86 (−1.48, −0.24)
Cd	0.04 (0.04–0.05)	0.06 (0.05–0.08)	0.05 (0.04–0.07)	0.19	0.10	0.10	0.98	0.36 (−0.07, 0.79)	0.35 (−0.07, 0.77)	−0.004 (−0.36, 0.36)
Cr	0.05 (0.04–0.44)	0.48 (0.29–1.47)	0.43 (0.15–0.62)	0.18	0.08	0.12	0.78	1.18 (−0.15, 2.52)	1.03 (−0.28, 2.34)	−0.16 (−1.28, 0.96)
Cu	19.9 (12.0–30.8)	15.4 (4.29–67.2)	33.4 (21.6–62.1)	0.43	1.00	0.32	0.25	0.003 (−1.01, 1.02)	0.5 (−0.50, 1.49)	0.49 (−0.36, 1.34)
Fe	3.46 (3.42–3.82)	5.72 (4.16–12.1)	3.50 (3.42–4.08)	0.03	0.02	0.47	0.04	0.73 (0.14, 1.31)	0.21 (−0.37, 0.79)	−0.52 (−1.01, −0.02)
Mn	1.39 (0.59–2.91)	0.77 (0.33–1.58)	0.53 (0.11–0.78)	0.01	0.46	0.007	0.02	−0.40 (−1.47, 0.68)	−1.48 (−2.54, −0.42)	−1.09 (−1.99, −0.18)
Ni	0.73 (0.27–13.2)	6.73 (3.16–9.21)	1.80 (0.44–2.98)	0.05	0.12	0.61	0.02	1.07 (−0.30, 2.44)	−0.34 (−1.69, 1.00)	−1.41 (−2.56, −0.27)
Pb	6.28 (5.12–11.7)	2.38 (1.15–3.65)	14.1 (7.91–32.0)	<0.001	0.02	0.21	<0.001	−1.18 (−2.20, −0.17)	0.62 (−0.37, 1.62)	1.81 (0.96, 2.66)
Sb	0.48 (0.39–0.91)	0.33 (0.13–0.64)	1.14 (0.66–1.76)	0.03	0.37	0.15	0.008	−0.39 (−1.25, 0.48)	0.61 (−0.24, 1.46)	1.00 (0.27, 1.72)
Sn	0.37 (0.35–0.47)	0.51 (0.39–0.70)	0.65 (0.35–1.00)	0.04	0.04	0.01	0.61	0.47 (0.01, 0.93)	0.57 (0.12, 1.02)	0.10 (−0.29, 0.48)
U	0.04 (0.04–0.05)	0.06 (0.05–0.08)	0.04 (0.04–0.05)	0.005	0.006	0.75	0.004	0.36 (0.11, 0.61)	0.04 (−0.21, 0.29)	−0.32 (−0.53, −0.11)
W	0.05 (0.04–0.06)	0.06 (0.05–0.08)	0.04 (0.04–0.05)	0.50	0.29	0.76	0.36	0.24 (−0.22, 0.70)	0.07 (−0.38, 0.52)	−0.18 (−0.56, 0.21)
Zn	1014 (699–2057)	1577 (916–2448)	704 (490–2366)	0.18	0.24	0.72	0.07	0.34 (−0.23, 0.92)	−0.10 (−0.66, 0.46)	−0.44 (−0.92, 0.04)
	Median (IQR) in OD			Overall p-value	Linear regression p-value			Beta value (95% CI)
	Fruit (n=18)	Tobacco (n=18)	Menthol (n=18)		Fruit vs. Tobacc	Fruit vs. Menthol	Tobacco vs. Menthol	Fruit vs. Tobacco	Fruit vs. Menthol	Tobacco vs. Menthol
Al	11.6 (7.06–17.4)	16.7 (9.41–25.1)	14.8 (6.94–29.2)	0.24	0.16	0.13	0.90	0.42 (−0.17, 1.00)	0.46 (−0.13, 1.04)	0.04 (−0.55, 0.63)
As	1.58 (1.38–2.00)	2.07 (1.59–3.40)	1.17 (0.68–1.37)	<0.001	0.07	0.04	<0.001	0.35 (−0.02, 0.71)	−0.39 (−0.76, −0.02)	−0.74 (−1.10, −0.37)
Cd	0.16 (0.11–0.29)	0.05 (0.05–0.18)	0.05 (0.05–0.28)	0.24	0.12	0.79	0.19	−0.68 (−1.54, 0.18)	−0.11 (−0.97, 0.75)	0.57 (−0.29, 1.43)
Cr	4.48 (1.49–62.5)	7.99 (4.89–15.0)	3.04 (2.20–8.17)	0.37	0.94	0.21	0.24	−0.04 (−0.95, 0.88)	−0.58 (−1.49, 0.34)	−0.54 (−1.45, 0.37)
Cu	247 (150–447)	615 (134–1305)	278 (61.6–689)	0.16	0.06	0.47	0.24	0.78 (−0.03, 1.58)	0.29 (−0.52, 1.10)	−0.48 (−1.29, 0.33)
Fe	159 (66.6–246)	194 (115.9–260)	38.5 (25.6–92.6)	<0.001	0.19	0.005	<0.001	0.45 (−0.23, 1.12)	−0.98 (−1.65, −0.30)	−1.42 (−2.10, −0.75)
Mn	33.4 (20.3–57.2)	51.4 (23.6–91.3)	21.9 (14.0–48.3)	0.04	0.12	0.30	0.01	0.38 (−0.10, 0.87)	−0.25 (−0.74, 0.23)	−0.63 (−1.12, −0.15)
Ni	1181 (811–2757)	1032 (40.6–2807)	852 (466–1901)	0.13	0.04	0.36	0.26	−0.93 (−1.84, −0.02)	−0.42 (−1.32, 0.49)	0.52 (−0.39, 1.42)
Pb	377 (166–588)	254 (120–676)	150 (67.7–519)	0.12	0.98	0.07	0.08	−0.01 (−0.70, 0.68)	−0.63 (−1.32, 0.06)	−0.62 (−1.31, 0.07)
Sb	3.14 (2.36–4.02)	3.54 (2.97–5.22)	4.29 (2.13–6.01)	0.41	0.49	0.18	0.52	0.15 (−0.28, 0.58)	0.29 (−0.14, 0.73)	−0.14 (−0.29, 0.58)
Sn	154 (12.6–309)	208 (43.4–385)	99.5 (11.6–256)	0.44	0.26	0.97	0.27	0.58 (−0.44, 1.59)	0.02 (−1.00, 1.03)	−0.56 (−1.57, 0.46)
U	0.05 (0.05–0.05)	0.05 (0.05–0.05)	0.05 (0.05–0.05)	0.16	0.21	0.52	0.06	−0.02 (−0.06, 0.01)	0.01 (−0.03, 0.05)	0.04 (−0.002, 0.08)
W	0.10 (0.05–0.17)	0.25 (0.11–0.58)	0.05 (0.04–0.13)	<0.001	0.005	0.36	<0.001	0.99 (0.32, 1.65)	−0.31 (−0.97, 0.36)	−1.29 (−1.96, −0.62)
Zn	3420 (2207–4551)	3149 (2233–5142)	2558 (1751–4324)	0.51	0.88	0.36	0.29	0.04 (−0.53, 0.61)	−0.26 (−0.83, 0.31)	−0.31 (−0.88, 0.27)