Table 3.

Median (interquartile range) metal concentrations (μg/kg) in aerosols by nicotine content.

	Median (IQR) in CD			Overall p-value	Linear regression p-value			Beta value (95% CI)
	0 mg/mL (n=7)	24mg/mL (n=30)	59 mg/mL (n=9)		0 vs. 24 mg/mL	0 vs. 59 mg/mL	24 vs. 59 mg/mL	0 vs. 24 mg/mL	0 vs. 59 mg/mL	24 vs. 59 mg/mL
Al	13.4 (6.93–14.4)	15.0 (9.18–32.2)	4.12 (4.05–4.40)	<0.001	0.23	0.03	<0.001	0.42 (−0.27, 1.11)	−0.96 (−1.79, −013)	−1.38 (−2.00, −0.75)
As	0.09 (0.09–0.10)	0.11 (0.09–0.16)	0.09 (0.09–0.09)	0.56	0.31	0.68	0.57	0.43 (−0.41, 1.26)	0.21 (−0.80, 1.22)	−0.22 (−0.98, 0.54)
Cd	0.05 (0.04–0.18)	0.06 (0.05–0.08)	0.04 (0.04–0.04)	0.04	0.28	0.01	0.04	−0.23 (−0.67, 0.20)	−0.66 (−1.18, −0.14)	−0.42 (−0.82, −0.03)
Cr	0.49 (0.28–0.69)	0.29 (0.04–0.88)	0.41 (0.34–0.57)	0.49	0.37	0.97	0.35	−0.65 (−2.09, 0.79)	−0.03 (−1.76, 1.70)	0.62 (−0.69, 1.92)
Cu	33.4 (26.3–45.2)	30.6 (17.8–76.6)	6.02 (4.05–7.88)	<0.001	0.90	0.002	<0.001	0.06 (−0.84, 0.95)	−1.73 (−2.81, −0.66)	−1.79 (−2.60, −0.98)
Fe	3.45 (3.42–3.90)	4.75 (3.66–7.55)	3.38 (3.36–3.42)	0.05	0.12	0.68	0.03	0.49 (−0.14, 1.11)	−0.16 (−0.91, 0.59)	−0.64 (−1.20, −0.08)
Mn	0.30 (0.10–0.68)	1.02 (0.57–1.99)	0.39 (0.20–0.53)	0.02	0.02	0.74	0.03	1.36 (0.21, 2.51)	0.23 (−1.15, 1.61)	−1.13 (−2.17, −0.09)
Ni	1.80 (0.95–2.75)	1.24 (0.34–4.60)	11.9 (10.7–22.7)	<0.001	0.98	<0.001	<0.001	−0.02 (−1.24, 1.21)	2.71 (1.24, 4.18)	2.73 (1.62, 3.84)
Pb	15.8 (11.0–35.5)	5.60 (2.55–13.8)	0.88 (0.57–1.15)	<0.001	0.01	<0.001	<0.001	−1.33 (−2.35, −0.30)	−2.96 (−4.19, −1.74)	−1.64 (−2.56, −0.71)
Sb	1.61 (1.20–2.04)	0.67 (0.35–1.17)	0.15 (0.11–0.53)	0.002	0.07	<0.001	0.008	−0.79 (−1.65, 0.07)	−1.87 (−2.90, −0.83)	−1.08 (−1.85, −0.30)
Sn	0.53 (0.40–0.76)	0.64 (0.40–0.80)	0.35 (0.34–0.35)	0.05	0.75	0.10	0.01	0.08 (−0.41, 0.56)	−0.48 (−1.06, 0.10)	−0.56 (−1.00, −0.12)
U	0.04 (0.04–0.05)	0.05 (0.05–0.07)	0.04 (0.04–0.04)	0.01	0.05	0.64	0.007	0.25 (−0.005, 0.50)	−0.07 (−0.38, 0.23)	−0.32 (−0.55, −0.09)
W	0.04 (0.04–0.05)	0.05 (0.04–0.07)	0.04 (0.04–0.04)	0.32	0.45	0.65	0.16	0.18 (−0.30, 0.66)	−0.13 (−0.70, 0.45)	−0.31 (−0.75, 0.12)
Zn	1125 (787–2366)	1412 (668–2627)	683 (597–864)	0.04	0.98	0.06	0.02	−0.007 (−0.59, 0.58)	−0.67 (−1.38, 0.03)	−0.67 (−1.20, −0.14)
	Median (IQR) in OD			Overall p-value	Linear regression p-value			Beta value (95% CI)
	0 mg/mL (n=18)	6 mg/mL (n=18)	24 mg/mL (n=18)		0 vs. 6 mg/mL	0 vs. 24 mg/mL	6 vs. 24 mg/mL	0 vs. 6 mg/mL	0 vs. 24 mg/mL	6 vs. 24 mg/mL
Al	14.7 (7.92–17.7)	13.4 (7.33–23.0)	15.3 (9.98–24.4)	0.80	0.91	0.53	0.61	0.03 (−0.57, 0.64)	0.19 (−0.42, 0.79)	0.16 (−0.45, 0.76)
As	1.47 (1.21–1.69)	1.57 (1.38–3.15)	1.86 (1.11–2.30)	0.61	0.47	0.82	0.34	0.15 (−0.27, 0.57)	−0.05 (−0.47, 0.37)	−0.20 (−0.62, 0.22)
Cd	0.05 (0.05–0.15)	0.23 (0.13–0.40)	0.05 (0.05–0.15)	0.002	0.001	0.73	0.003	1.34 (0.56, 2.12)	0.14 (−0.64, 0.92)	−1.21 (−1.99, −0.42)
Cr	5.17 (1.84–9.51)	8.19 (3.40–35.2)	5.97 (2.49–9.66)	0.61	0.32	0.57	0.67	0.46 (−0.46, 1.38)	0.26 (−0.66, 1.19)	−0.20 (−1.12, 0.73)
Cu	217 (95.7–428)	572 (110–1497)	370 (208–546)	0.19	0.07	0.40	0.32	0.75 (−0.07, 1.56)	0.34 (−0.47, 1.15)	−0.41 (−1.22, 0.41)
Fe	103 (45.4–194)	182 (106–206)	65.7 (32.6–4534)	0.56	0.30	0.81	0.43	0.40 (−0.38, 1.19)	0.09 (−0.69, 0.88)	−0.31 (−1.09, 0.47)
Mn	29.9 (20.2–48.3)	52.7 (17.7–91.4)	32.7 (20.3–54.8)	0.32	0.20	0.95	0.18	0.33 (−0.18, 0.83)	−0.01 (−0.52, 0.49)	−0.34 (−0.84, 0.16)
Ni	882 (501–1643)	920 (489–2358)	1793 (881–2970)	0.08	0.68	0.03	0.08	0.19 (−0.71, 1.09)	0.98 (0.08, 1.88)	0.79 (−0.11, 1.69)
Pb	175 (117–488)	619 (92.1–827)	195 (151–398)	0.47	0.34	0.86	0.26	0.34 (−0.37, 1.05)	−0.06 (−0.77, 0.65)	−0.41 (−1.12, 0.30)
Sb	3.07 (2.06–4.52)	4.64 (3.42–6.75)	2.59 (2.18–4.29)	0.007	0.005	0.82	0.009	0.59 (0.19, 0.99)	0.05 (−0.36, 0.45)	−0.54 (−0.95, −0.14)
Sn	171 (14.3–290)	99.5 (51.3–319)	134 (9.85–369)	0.50	0.41	0.76	0.26	0.42 (−0.60, 1.44)	−0.16 (−1.18, 0.86)	−0.58 (−1.60, 0.44)
U	0.05 (0.05–0.05)	0.05 (0.05–0.05)	0.05 (0.05–0.05)	0.12	0.30	0.30	0.54	−0.02 (−0.05, 0.02)	0.02 (−0.01, 0.05)	0.03 (0.001, 0.06)
W	0.19 (0.05–0.30)	0.08 (0.05–0.15)	0.12 (0.05–0.17)	0.59	0.40	0.94	0.36	−0.32 (−1.08, 0.44)	0.03 (−0.73, 0.79)	0.35 (−0.41, 1.11)
Zn	2346 (1799–3804)	3913 (2624–6279)	3039 (2032–4240)	0.55	0.28	0.62	0.55	0.31 (−0.26, 0.88)	0.14 (−0.43, 0.71)	−0.17 (−0.74, 0.40)