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. 2022 May 23;15:3053–3063. doi: 10.2147/JIR.S362006

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© 2022 Jung et al.

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Mild, LPS-induced inflammation does not cause the infiltration of peripheral immune cells. Representative images showing the number of CCR2-RFP⁺ cells and immunostaining for the microglial marker Iba-1 (green) in the indicated brain regions of CCR2-RFP mice injected with saline or i.p.-administered a single or 2 daily doses of LPS. Yellow arrow heads indicate CCR2-RFP⁺ cells.

Abbreviations: CA1, cornu ammonis 1; LHb, lateral habenula; NAcsh, nucleus accumbens shell; and VTA, ventral tegmental area.