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. 2022 May 27;17(5):e0247629. doi: 10.1371/journal.pone.0247629

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© 2022 de Oliveira Franco et al

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Fig 2 — Timeline assessments. CPM-test: condition pain modulation test; fNIRS: functional near-infrared spectroscopy. Pain VAS: Pain visual-analog scale. NPS: numeric pain scale. QST: Quantitative Sensory Testing. T0: mean temperature (three measurements per individual) at which the subjects reported a pain score of 6/10 on the NPS (0–10) during the QST before the heterotopic stimulus. T1: temperature equivalent to T0 but applied during hand water cold immersion. NPS(T0): NPS pain score during application of T0. NPS(T1): NPS pain score during application of T1.