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SBO, but not DTX alone, induced the activation of reactive oxygen species (ROS) in NSCLC cells. (a,b) A549 and H23 cells were treated with SBO at indicated concentrations and/or DTX for 24 h. DCFH-DA assay was performed to determine intracellular ROS level using flow cytometry. (c) Histograms represent the statistically quantified ROS production (MFI, mean fluorescence intensity). Data are the mean ± SD; * p < 0.05 vs. the corresponding control.
