Table 1.

Major-bioactive compounds in Seabuckthorn and their properties.

	Seabuckthorn Active Compounds	Medicinal Properties	References
1.	Tocopherols	Lipid-soluble antioxidant, inhibits oxidative stress, promising diet for Alzheimer’s disease (AD) prevention, may lower cholesterol levels	[7,26]
2.	Carotenoids	Beneficial antioxidant, wound healing through stimulation of angiogenesis, collagen synthesis, epithelialization	[27]
3.	Vitamin C	Antioxidant, acts as an enzymatic cofactor and maintains tissue integrity, and accelerates the formation of skin, epithelial, and endothelial barriers and collagen synthesis	[28,29]
4.	Vitamin B complex (B1, B2, and B6)	Increases the regeneration of axons and neuronal survival, promotes cell repair	[16]
5.	Polyphenolic compounds	Antioxidant, cytoprotective, hepatoprotective, wound healing	[13,14]
6.	Phytosterols	Stimulates microcirculation in the skin, exerts anti-ulcer, anti-atherogenic, and antitumor effects, modulation of the inflammatory process	[11]
7.	Polyunsaturated fatty acids (PUFA)	Immunomodulatory, neuroprotective, anticancer	[30]
8.	Zinc	Capable of improving the blood circulation, anticancer effect, cofactor for a number of enzymes, enhances the utilization of vitamin A	[31]