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. 2022 May 11;23(10):5367. doi: 10.3390/ijms23105367

Figure 6.

Figure 6

Relative mRNA levels of microglial phagocytic receptors and inflammation factors in microglia cells after knockdown of Trem2. BV2 microglia were treated with or without CBD (5 μM) after 12 h, and mRNA levels were determined by qPCR. The data are represented as the mean ± SEM (n = 4). * p < 0.05, ** p < 0.01, and *** p < 0.001 are compared with wild type treated with Aβ (1 μg/mL) by Tukey’s test; # p < 0.05, ## p < 0.01, and ### p < 0.001 mean CBD + Aβ with or without siRNA by Student’s t-test. $ p < 0.05, $$ p < 0.01, and $$$ p < 0.001 mean CBD knockdown of Trem2 with or without CBD by Student’s t-test.