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. 2022 May 13;23(10):5463. doi: 10.3390/ijms23105463

Table 1.

List of AMPs approved by the FDA as medicines.

Name of AMP Structure of AMP Mechanism of Action Reference
Gramicidin Linear, forms a spiral Pore formation from dimers [87]
Colistin Cyclic lipopeptide Membrane-lytic peptide [88]
Daptomycin Cyclic lipopeptide Membrane-lytic peptide [89]
Vancomycin Lipoglycopeptide Inhibitor of cell wall synthesis [90]
Oritavancin Lipoglycopeptide Dual-mechanism: membrane-lytic peptide and inhibitor of cell wall synthesis [91]
Dalbavancin Lipoglycopeptide Inhibitor of cell wall synthesis
Telavancin Lipoglycopeptide Dual-mechanism: membrane-lytic peptide and inhibitor of cell wall synthesis
Teicoplanin Lipoglycopeptide Inhibitor of cell wall synthesis [92]