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hsa_circ_0006692 played its roles via sponging hsa-miR-205-5p and regulating CDK19. (A) Sequence alignment of hsa-mir-205-5p with putative binding sites in circ-0006692 and CDK19 wild-type and mutant regions; (B–E) Double Luciferase Report analysis showed that hsa-mir-205-5p mimics reduced the fluorescence intensity of HEK293T or A549 cells transfected with circ-0006692-Wt or CDK19-Wt rather than circ-0006692- Mut or CDK19-Mut vector; ***p < 0.001; **** p < 0.0001.
