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. 2022 May 10;13(5):846. doi: 10.3390/genes13050846

Figure 6.

Figure 6

Enhancement of CDK19 was critical for circ-0006692-mediated malignant behaviors. (A,B) CDK19 expression in A549 cells in the rescue assay via RT-PCR and WB. (C,D) MTS assay and colony formation of A549 cells. (H,I) Wound healing assay of A549 cells; (J) Transwell invasive assay of A549 cells; (F,G) The expression levels of proliferation-associated-genes of BCL-2, CCND1, and PCNA measured by qRT-PCR and WB; (K) The expressions of EMT-associated-genes MMP7, VIMENTIN, CDH1, and CDH2 demonstrated by Western blotting; (E) Cell cycle distribution of A549 cells by FACS; ** p < 0.01; *** p < 0.001, **** p < 0.0001.