Figure 2.

Functional enrichment analysis of hub genes from brown and blue modules. Network representation of select enriched biological processes and pathways among the intramodular hubs from the brown and the blue candidate modules. An edge between a gene (oval node) and a functional annotation (rectangular node) indicates the membership of that gene to that annotation term. Enriched terms are represented as blue color rectangles. Upregulated hub genes of brown module are in pink color while the downregulated genes from the blue module are in green color. Novel fibrotic candidates are highlighted using blue color solid node borders while the secreted novel hubs are highlighted with zig-zag blue borders. Network is generated using Cytoscape application.