Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 May 13;23(10):5447. doi: 10.3390/ijms23105447

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

CRABP2 as a novel candidate for IPF. CRABP2 is significantly upregulated in IPF (A) and is negatively correlated with lung function (FVC and DL_CO; B). Additionally, CRABP2 is differentially expressed in acute exacerbation (C) and shows a gradient level upregulation in three stages of IPF, namely, early (IPF1), progressive (IPF2), and advanced (IPF3) stages (D). CRABP2 is enriched in both epithelial (aberrant basaloid or KRT5-/KRT17+ and goblet cells) and mesenchymal (fibroblast, myofibroblast, HAS1-high fibroblasts, and PLIN2+ fibroblasts) cells (E,F).