Table 3.

Adjusting for the Non-Independence of Data on Group Differences.

	Adjusted Beta (Risk Group)	p-Value	Adjusted Beta (Risk-by-Sex)	p-Value
Unadjusted for Familial Correlations	−0.59	0.006	−0.02	0.95
Corrected with GEE	−0.567	0.002	−0.006	0.98
Corrected with Mixed Model	−0.3	0.0057	0.003	0.94

The identified voxel was located on the dorsal aspect of the left hippocampal head. GEE = Generalized Estimating Equations; Mixed Model = linear mixed effects model. The findings indicate that familial relatedness did not substantially alter the main effect of risk or the interaction of risk-by-sex on surface distances.