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Graphical representation of possible meiotic HORMAD conformations, mediated by Pch2/TRIP13: SC (self-closed)-HORMAD; U(unbuckled)-HORMAD; and C(closed)-HORMAD bound to a CM motif on an interactor, such as an axis component. We note that, in addition to the HORMAD binding to its own CM in cis, a trans conformation is also possible.
