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. 2022 May 13;13(5):876. doi: 10.3390/genes13050876

Table 2.

Correlation analysis between EZH2 and biomarkers of immune cells in HCC determined using the GEPIA and TIMER databases.

GEPIA TIMER
R p R p
B cells CD19 0.110 1.10 × 10−1 0.244 1.92 × 10−6
CD79A 0.083 7.90 × 10−5 0.131 1.18 × 10−2
CD8+ T cells CD8A 0.200 1.40 × 10−5 0.180 5.05 × 10−4
CD8B 0.220 7.70 × 10−3 0.168 1.17 × 10−3
CD4+ T cells CD4 0.140 8.20 × 10−1 0.217 2.44 × 10−5
M1 macrophages NOS2 −0.012 0.00 × 10−0 0.003 9.48 × 10−1
IRF5 0.440 5.00 × 10−1 0.482 5.97 × 10−23
PTGS2 0.035 2.80 × 10−3 0.088 9.22 × 10−2
M2 macrophages CD163 0.160 2.40 × 10−4 0.101 5.21 × 10−2
VSIG4 0.190 2.00 × 10−3 0.100 5.41 × 10−2
MS4A4A 0.160 8.30 × 10−1 0.102 5.07 × 10−2
Neutrophils CEACAM8 0.011 2.40 × 10−11 0.094 6.95 × 10−2
ITGAM 0.340 2.20 × 10−1 0.289 1.44 × 10−8
CCR7 0.064 2.40 × 10−5 0.083 1.10 × 10−1
Dendritic cells HLA-DPB1 0.220 9.00 × 10−2 0.154 2.91 × 10−3
HLA-DQB1 0.088 1.70 × 10−5 0.146 4.87 × 10−3
HLA-DRA 0.220 1.20 × 10−4 0.167 1.22 × 10−3
HLA-DPA1 0.200 7.40 × 10−4 0.158 2.28 × 10−3
CD1C 0.170 6.50 × 10−8 0.114 2.85 × 10−2
NRP1 0.280 1.10 × 10−6 0.263 2.67 × 10−7
ITGAX 0.250 1.10 × 10−1 0.348 5.15 × 10−12

HCC: hepatocellular carcinoma; EZH2: Enhancer of Zeste Homolog 2; p values less than 0.05 are shown in bold.