Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Amino acid residues in DIO1 possibly involved in a proton relay pathway. (A). Schematic representation of the conserved hydrogen-bond network. Arrows indicate electron shifts for a potential proton relay. (B). Western blot analysis of DIO1 in stable COS7 clones directed against the Flag-tag. (C). 5′-deiodinase activities of DIO1 variants expressed in COS7 cells. 20 mM DTT served as reducing co-factor. SD: standard deviation.
