Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 May 27;3(7):e493–e502. doi: 10.1016/S2666-5247(22)00090-8

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2022 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY-NC-ND 4.0 license

Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.

PMC Copyright notice

Correlation of neutralisation titres and serology assays

(A) Correlation of NT₅₀ (x-axis) with serological assay values (y-axis) obtained at visit 1 and visit 5 for each participant; statistical significance was determined with the Spearman correlation test for samples obtained at visit 1 and visit 5 independently, with Spearman's r and respective 95% CIs as indicated; dotted lines indicate serological assay thresholds. (B) Correlation of fold change (visit 1 to visit 5) of NT₅₀s with corresponding fold change in serological assay values for indicated serology assays. Statistical significance was determined using the Spearman correlation test, with Spearman's r and respective 95% CIs as indicated. Dotted lines at x=1 and y=1 indicate unchanged assay results over time. For the cPass assay, the serum dilution at which 50% signal inhibition was achieved was defined as 50% surrogate virus neutralisation titre (sVNT₅₀). AU=arbitrary unit. COI=confidence interval. N=nucleocapsid. NT₅₀=half-maximal neutralisation titre. RBD=receptor binding domain. S=spike protein. S/C=ratio over threshold value. U=unit.