Table 2.
Gene mutations and associated specific disease.
| Gene Mutation and Diagnosis | Case Numbers |
Idylla Positive |
Idylla Negative |
Cases with Extra Mutations |
Cases with Extra and Tier 1 Mutations Not Detected by Idylla |
|---|---|---|---|---|---|
| BRAF melanoma | 27 | 21 (78%) | 6 (22%) | 8 (30%) | 2 (8%) |
| NRAS melanoma | 28 | 26 (93%) | 2 (7%) | 12 (43%) | 5 (18%) |
| BRAF HCL | 11 | 10 (91%) | 1(9%) | 3 (27%) | 3 (27%) |
| BRAF CRC | 53 | 51 (96%) | 2 (4%) | 17 (32%) | 9 (17%) |
| KRAS CRC | 65 | 62 (95%) | 3 (5%) | 24 (37%) | 17 (26%) |
| NRAS CRC | 3 | 2 (66%) | 1 (33%) | 2 | 2 (66%) |
| EGFR lung adenocarcinoma | 65 | 56 (86%) | 9 (7%) | 21 (32%) | 7 (11%) |
| KRAS lung adenocarcinoma | 158 | 147 (93%) | 11 (7%) | 25 (16%) | 12 (8%) |