Table 1.

The frequency of MYD88^L265P in B-cell lymphoproliferative disorders.

Entity	N	MYD88L265P Range	References
Waldenström’s macroglobulinemia	470	67–100%	[11,12,13,14,15,50,51,52,56]
IgM-MGUS	164	10–87%	[11,12,13,14,15,46]
MALT lymphoma	105	0–9%	[23,50,54]
MZL	325	0–21%	[11,12,13,14,15,50,53,54]
Multiple myeloma (including IgM)	188	0%	[11,13,14,15,51,53,55,56]
Chronic lymphocytic leukemia	412	0–43% 1	[13,14,15,24,52,53,56]

¹ Forty-three percent in a series of CLL with an IgM component. IgM-MGUS, IgM monoclonal gammopathy of undetermined significance; MALT, mucosa-associated lymphoid tissue; MZL, marginal zone lymphoma.