Figure 1.

Number of patients in Nicaragua with recurrent P. vivax infections, categorized by latency, from 2013 to 2018. Interval between the primary infection (PI) and the first recurrence (R1) (in blue; median = 207/IQR, 113–331), between R1 and R2 (in orange; median = 109/IQR, 62–200), between R2 and R3 (in grey; median = 71/IQR, 54–132), and between R3 and R4 (in yellow; median = 64/IQR, 59–142). The latency of recurrent cases decreased as the number of R episodes increased (χ² (3) = 136.2, p < 0.001).