Table 1.

Schematic description of the MC and Mɸ receptors, ligands, and functions mentioned in this review.

Receptor	Ligand	Expression	Function
TLR2	Bacterial, viral, fungal and parasites lipids, proteins, polysaccharides	MC and M1 M2	Pro-inflammatory cytokines production, degranulation [28,29,30], IL-10, 15-LO [30]
TLR4	Bacterial and viral proteins	MC and M1 M2	Pro-inflammatory cytokines production, degranulation [25,31,32,33,34], IL-10, 15-LO, 15-HETE lipoxins [34]
FcεRI	Allergens	MC	Allergic reaction [13,17,35]
CD14	Endotoxin receptor	Mɸ	Pro-inflammatory cytokine production [36,37]
F4/80	Marker mouse	Mɸ	Differentiation, induction of CD8+ T regulatory cells [10]
c-KIT	SCF	MCs	Migration, differentiation, and survival [12,13,21]
NK-R1	Substance P	Mɸ	Pro-inflammatory cytokines, NO, ROS, production. Induction of COX-2 activity [38]
MRGPR	Substance P	MC	Pro-inflammatory cytokine production, histamine and protease release [23]