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. 2021 Mar 31;57(2):314–320. doi: 10.1055/s-0041-1724076

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Sociedade Brasileira de Ortopedia e Traumatologia. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commecial purposes, or adapted, remixed, transformed or built upon. ( https://creativecommons.org/licenses/by-nc-nd/4.0/ )

This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License, which permits unrestricted reproduction and distribution, for non-commercial purposes only; and use and reproduction, but not distribution, of adapted material for non-commercial purposes only, provided the original work is properly cited.

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Fig. 3 — Atividade mitocondrial das SFCs após tratamento inibidor de Smad3. A atividade de SFC W/O OA reduziu após 24 horas de tratamento usando inibidor Smad3 ( p = 0,046), mas aumentou após 48 horas ( p = 0,0002) e 72 horas ( p = 0,006). Por outro lado, as SFCs do grupo W/OA apresentaram redução da atividade somente após 72 horas na presença do inibidor Smad3 ( p = 0,0102), mas não foram encontradas diferenças após 24 e 48 horas ( p > 0,05).