Table 2.
Treatment costs
| References | Country | Cost | US$ (2020) | € (2020) |
|---|---|---|---|---|
| Cortesi et al. [15] | Italy |
Mean per patient-month cost of pharmacological therapy (minimum–maximum) Mean per patient-month cost of non-pharmacological therapy, e.g. emollients, galenic formulations, and ultraviolet irradiation (minimum–maximum) |
$28.34 ($0–$144.92) $29.21 ($0–$161.71) |
€20.15 (€0–€103.04) €20.77 (€0–€114.98) |
| Fowler et al. [16] | USA | Per patient monthly costs (mean ± SE) | ||
|
Prescription drugs Outpatient services |
$165.02 (±$8.47) $255.71 (±$20.02) |
€117.33 (±€6.02) €181.81 (±€14.23) |
||
| NICE TA177 [12] | UK | Acquisition cost (per cycle of therapy) | ||
|
Alitretinoin Ciclosporin PUVA Azathioprine |
$716.17 $307.16 $960.14 $31.34 |
€509.20 €218.39 €682.66 €22.28 |
||
| Refractory costs for alitretinoin, ciclosporin, PUVA, azathioprine (per 4 weeks) | $20.60 | €14.65 | ||
| Supportive costs (per 4 weeks) | ||||
|
Alitretinoin Ciclosporin PUVA Azathioprine |
$101.92 $99.88 $91.50 $95.22 |
€72.47 €71.01 €65.06 €67.70 |
||
| Remission costs (4 weeks) | ||||
|
Alitretinoin Ciclosporin PUVA Azathioprine |
$9.70 $20.60 $20.60 $20.60 |
€6.90 €14.65 €14.65 €14.65 |
||
| Blank et al. [11] | Switzerland | Mean cost per month | ||
|
Alitretinoin (30 mg capsules) Emollients |
$702.44 $36.49 |
€499.43 €25.94 |
||
| Average cost per month | ||||
|
Patients taking alitretinoin (30 mg) Patients taking placebo Patients clear or almost clear maintenance Severe non-responders |
$797.72 $75.01 $46.63 $191.57 |
€567.18 €53.33 €33.15 €136.21 |
||
| Augustin et al. [14] | Germany | Yearly treatment costs | ||
|
Topical corticosteroids Emollients |
$599.05 $178.40 |
€425.92 €126.84 |
||
PUVA psoralen-ultraviolet A therapy, SE standard error