The direct and indirect economic costs of chronic hand eczema (CHE) are comparable with other dermatological conditions.

Ongoing development of new therapies means the direct economic burden of CHE may be higher than estimated in this literature review, since some of the included studies are more than 10 years old.

There are few studies of the economic cost burden of absenteeism, presenteeism and job change in CHE.

The societal costs of CHE are likely underestimated.