Table 2.
List of AMR or it's associated identified metabolites with peak intensity.
| S.no. | Metabolite | Method of detection (peak intensity) | ||
|---|---|---|---|---|
| SC | FTC | FTC + SC | ||
| Cell wall biosynthesis | ||||
| 1 | Carnitine | 413.60 | 210.37 | 234.03 |
| 2 | Glutathione (oxidized) | 2261.78 | 3313.24 | 2277.07 |
| 3 | Palmitate | 328,732.17 | 175,542.63 | 32,988.38 |
| 4 | U-D-G glucose | 12,507.41 | 7548.63 | 9292.17 |
| 5 | Pantothenic acid | 435.51 | 486.74 | 634.83 |
| 6 | Phthalic acid | 1699.60 | 1608.78 | 2197.18 |
| 7 | Nonanoate | 1126.71 | 1016.35 | 759.79 |
| 8 | Stearate | 100,943.83 | 99,892.75 | 83,283.90 |
| 9 | Benzophenone | 1243.86 | 1301.05 | 1341.30 |
| 10 | Betaine | 18,091.82 | 16,474.18 | 14,153.99 |
| 11 | Oleamide | 4671.00 | 4992.14 | 4529.73 |
| 12 | Uridine monophosphate | 720.08 | 415.26 | 713.81 |
| 13 | Uridine diphosphategalactose | 338.61 | 494.66 | 591.62 |
| 14 | 3-(2-Hydroxyphenyl)propanoate | 449.12 | 366.04 | 379.49 |
| 15 | Octadecanedioic acid | – | 554.22 | 1721.41 |
| 16 | Trehalose | – | 1101.25 | 637.29 |
| 17 | l-Aspartate | – | 265.92 | 617.25 |
| 18 | l-lysine | – | 213.47 | 306.04 |
| 19 | l-Alanine | 609.26 | – | – |
| 20 | Mevalonate | – | 57.02 | – |
| 21 | Aspartic acid | – | 567.81 | – |
| 22 | Galactose | – | 300.01 | – |
| 23 | Pantothenate | – | 278.07 | – |
| 24 | Ala-leu | – | – | 1082.98 |
| 25 | Sucrose | – | – | 10,280.49 |
| 26 | Maltose | – | – | 1286.16 |
| 27 | Palmitoleic acid | – | – | 2738.64 |
| 28 | UDP-N-Acetylglucosamine | – | – | 1655.90 |
| 29 | Uridine-5-monophosphate | – | – | 3243.20 |
| 30 | Raffinose | – | – | 439.59 |
| Total | 15.00 | 22.00 | 25.00 | |
| Cell membrane | ||||
| 31 | Caprylate | 551.49 | 548.69 | 699.02 |
| 32 | d-pantothenic acid | 658.56 | 702.47 | 776.97 |
| 33 | l-Glutathione oxidized | 7492.62 | 8310.20 | 5288.27 |
| 34 | 10-Hydroxydecanoate | 539.80 | 825.35 | 654.67 |
| 35 | Glycolic acid | 437.88 | − | 540.63 |
| 36 | Hexadecanedioic acid | − | 226.35 | 386.67 |
| 37 | Heptadecanoate | − | 136.80 | − |
| 38 | Biotin | − | 1307.61 | − |
| 39 | Uridine diphosphate glucuronic acid | − | 2243.12 | − |
| 40 | Glutathione | − | − | 1107.25 |
| Total | 5.00 | 8.00 | 7.00 | |
| Nucleotide metabolism | ||||
| 41 | Adenosine | 4086.96 | 4782.98 | 5018.04 |
| 42 | Adenosine-3-monophosphate | 483.44 | 382.52 | 1058.15 |
| 43 | Hypoxanthine | 3212.21 | 944.57 | 571.10 |
| 44 | Ribose | 644.30 | 643.42 | 559.87 |
| 45 | Adenine | 387.66 | 214.02 | 367.07 |
| 46 | Adenosine monophosphate | 1342.57 | 1141.64 | 2540.13 |
| 47 | Guanine | 3449.86 | 7865.84 | 3635.78 |
| 48 | Guanosine | 543.53 | 349.92 | 1084.45 |
| 49 | Uracil | 941.17 | 1179.20 | − |
| 50 | 4-Aminobenzoic acid | 393.54 | − | 455.21 |
| 51 | Inosine | − | 363.91 | 1702.13 |
| 52 | Ump | − | 214.79 | 503.96 |
| 53 | Cytidine monophosphate | − | 283.23 | 640.49 |
| 54 | Cytosine | 508.32 | − | − |
| 55 | Uridine | 343.83 | 427.97 | 843.25 |
| 56 | Cytidine diphosphate | − | − | 379.63 |
| Total | 13.00 | 14.00 | 14.00 | |
| Protein synthesis | ||||
| 57 | d-(-)-3-Phosphoglyceric acid | 854.48 | 521.40 | 980.56 |
| 58 | l-Arginine | 378.60 | 339.70 | 427.68 |
| 59 | l-Glutamic acid | 4963.65 | 3184.31 | 1901.57 |
| 60 | Alloisoleucine | 988.76 | − | 794.83 |
| 61 | Isoleucine | 2618.71 | − | 2912.32 |
| 62 | NAD | − | 15,879.67 | 3470.52 |
| 63 | Glutamic acid | − | 1594.75 | 197.33 |
| 64 | l-Proline | 3921.73 | − | − |
| 65 | Pipecolate | 479.67 | − | − |
| 66 | Nicotinate | 475.13 | − | − |
| 67 | Tryptophan | − | 463.37 | − |
| 68 | Leucine | − | 2952.60 | − |
| 69 | 4-Hydroxyphenylacetic acid | − | − | 391.96 |
| 70 | Dethiobiotin | − | − | 331.84 |
| Total | 8.00 | 7.00 | 9.00 | |