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. 2022 May 27;2:60. doi: 10.1038/s43856-022-00122-7

Fig. 3. Impact of penile-vaginal sex on cervico-vaginal soluble immune factors.

Fig. 3

Concentration of IP-10 (pg/ml) at baseline and 1 h, 72 h after (a) condomless sex (N = 29), (b) condom-protected sex (N = 8). Concentration of IL-1α (pg/ml) at baseline and 1 h and 72 h after (c) condomless sex (N = 29), (d) condom-protected sex (N = 8). The red dotted line shows the lower level of detection (LLODs). The red numbers illustrate the median cytokine concentration at each visit. See methods for detailed information on LLOD values for each cytokine. Statistical comparisons were performed using Wilcoxon Signed Ranked test. Summary of the median difference and interquartile range of undiluted cervico-vaginal cytokines concentrations from baseline to 1 h post (e) condomless sex and (f) condom-protected sex. Summary of the median difference and interquartile range of undiluted cervico-vaginal cytokines concentrations from baseline 72 h post (g) condomless sex and (h) condom-protected sex. Cytokine values were log10 transformed only for the presentation purpose, and statistical comparisons were performed using Wilcoxon Signed Ranked test. *p < 0.05, **p < 0.01, ***p < 0.001. The box plots represent the median difference from baseline, with interquartile and minimum to maximum ranges.