Table 2.

Histology for patient-derived glioblastoma tumor slices in Figures 2B and S6

	Figure 2B (top), sparse	Figure 2B (bottom), dense
Histology	% of total H&E slide	% of total H&E slide
Tumor	40	90
Stroma	50	10
Necrosis	10	<5
Immune cells	10	<5
Stromal cells	40	<5

Qualitative scores from clinical pathology for each tumor slice by the total fraction of tumor stroma, necrosis, immune cell, and stromal cell content (i.e., non-cancer cells within the stroma vs tumor matrix). The fraction of stroma includes tumor matrix proteins (TMPs) as well as the stromal cells (e.g., fibroblasts). Stromal cell content is calculated separately, and can be extrapolated to determine the TMPs (e.g., collagen/fibronectin and so forth) vs. stromal, non-cancer cells.