Fig. 1.

Study timeline and acute exercise trial procedures. Participants completed a VO_2peak test and 20 km time trial before supplementing with MitoQ or a placebo for 10 days. Participants then completed a bout of high-intensity interval exercise (10 × 60 s at VO_2peak power output). Muscle biopsies were collected before exercise, immediately after exercise, and 3 h after exercise. Blood samples were collected before exercise and immediately, 30 min, and 1, 2, and 3 h after exercise. Participants then completed 9 sessions of high-intensity interval training before repeating the 20 km time trial and VO_2peak test. A muscle biopsy and blood sample were collected on completion of training.