Fig. 2.

The effect of MitoQ supplementation and exercise on systemic and skeletal muscle markers of oxidative stress. A) Baseline plasma protein carbonyls following 10 days of MitoQ or placebo supplementation. B) Plasma protein carbonyls immediately (Post), 1 h (1 h), and 2 h (2 h) after exercise presented as fold change from pre-exercise. C) Baseline skeletal muscle mtDNA damage following 10 days of MitoQ or placebo supplementation. D) Skeletal muscle mtDNA damage immediately and 3 h (3 h) after exercise. E) Baseline blood reduced glutathione (GSH) concentration following 10 days of MitoQ or placebo supplementation. F) Blood GSH concentration immediately, 30 min, and 1 h after exercise presented as fold change from pre-exercise. G) Baseline skeletal muscle 4-HNE levels following 10 days of MitoQ supplementation. H) Skeletal muscle 4-HNE immediately and 3 h after exercise presented as fold-change from pre-exercise. Triangles and circles represent individual values. Differences in markers of oxidative stress at baseline were analysed using unpaired Student's t-test. Main two-way repeated measures ANOVA effects are given in figures B, D, and F. Data are presented as mean ± SD.