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. 2022 May 28;22:364. doi: 10.1186/s12888-022-04008-9

Table 9.

Opinion of the scientific steering committee – clozapine resistance

• Augmentation with aripiprazole should be considered in patients with TRS treated with clozapine in case of persistence of symptoms; this is of interest when negative symptoms persist
• Augmentation with aripiprazole should be attempted even in patients who did not respond to aripiprazole monotherapy prior to clozapine treatment