Table 2.

Thyroid function and autoimmune parameters in all women and according to the foetal gender.

Gestational age and thyroid function/TAI data	All women	Female foetus	Male foetus	P
Continuous dataa
Categorical data (n (%))	n = 1663	n = 847 (51%)	n = 816 (49%)
Gestational age at blood sampling (weeks)	13 (11–17)	13 (11–17)	13 (11–17)
Gestational age at blood sampling (<9 >13 weeks)	880 (52.9%)	449 (53.0%)	431 (52.8%)
TSH (mIU/L)	1.44 (0.89–2.10)	1.40 (0.89–2.04)	1.49 (0.89–2.18)	0.022
<0.06 mIU/L	42 (2.5%)	26 (3.1%)	16 (2.0%)	0.149
0.06–2.50 mIU/L	1335 (80.3%)	693 (81.8%)	642 (78.7%)	0.108
2.51–3.74 mIU/L	203 (12.2%)	90 (10.6%)	113 (13.8%)	0.045
>3.74 mIU/L	83 (5.0%)	38 (4.5%)	45 (5.5%)	0.336
FT4 (pmol/L)b	14.2 (12.9–15.4)	14.2 (12.9–15.4)	12.9 (12.9–15.4)	0.708
Isolated hypothyroxinaemiab/c	11 (0.7%)	4 (0.5%)	7 (0.9%)	0.337
TPOAb (kIU/L)	28 (28–38)	28 (28–37)	29 (28–38)	0.228
TAI (TPOAb ≥ 60 kIU/L)	116 (7.0%)	50 (5.9%)	66 (8.1%)	0.079

Bold indicates statistical significance.

^aContinuous data are expressed as median (IQR range); ^bcalculated on 1646; ^cnormal TSH level and FT4 < 10.29 pmol/L.

TSH, thyrotropin; FT4, free thyroxine; TPOAb, thyroid peroxidase autoantibodies; TAI, thyroid autoimmunity.