Table 1. Summary of docking of antidepressant and anti-inflammatory drugs to TDO and IDO.

Antidepressant drugs docking to			Anti-inflammatory drugs docking to
Drug	TDO	IDO	Drug	TDO	IDO
Venlafaxine	+	-	Aspirin	-	+
Tianeptine	+	-	Salicylate	+	+
Amoxepine	+	-	Mefenamic acid	-	+
Paroxetine	+	-	Indomethacin	-	+
Moclobemide	+	-	Celecoxib	-	-
Fluvoxamine	+	-	Diclofenac	-	+
Ketamine	-	-	3-Hydroxy	-	-
Pargyline*	-		4-Hydroxy	-	-
			4,5-Dihydroxy	-	-

^*Does not inhibit TDO nor act as antidepressant.