Table 2.
Single unit composition of the fast release formulations / sustained release formulations containing fibers and diameter of the tablet obtained.
| Ingredients | Fast Release Formulations | Sustained Release Formulations | ||||
|---|---|---|---|---|---|---|
| Mfb4c6 | Cfb4c10 | Mfb4c1 | Mfb4c3 | Cfb4c6 | Cfb4c9 | |
| Mfb4 (corresponding 7.5 mg of meloxicam) | 33.0 mg | - | 33.0 mg | 33.0 mg | - | - |
| Cfb4 (corresponding 6.25 mg of carvedilol) | - | 27.5 mg | - | - | 27.5 mg | 27.5 mg |
| Sodium starch glycolate | 50.0 mg | - | - | - | - | |
| Microcrystalline cellulose | 75.0 mg | 100.0 mg | - | - | - | |
| Cross-linked polyvinylpyrrolidone | - | 50.0 mg | - | - | - | |
| HPMC K4M | - | - | 10.0 mg | 30.0 mg | 45.0 mg | 33.0 mg |
| Mannitol | - | - | - | - | 70.0 mg | 70.0 mg |
| Magnesium stearate | 1.0 mg | 1.0 mg | 1.0 mg | 1.0 mg | 1.0 mg | 1.0 mg |
| Total weight | 159.0 mg | 178.5 mg | 44.0 mg | 64.0 mg | 143.5 mg | 131.5 mg |
| Diameter of tablet | 8 mm | 8 mm | 5 mm | 6 mm | 8 mm | 8 mm |