Table 4.

Results of mathematical models of release kinetics (zero-order, first-order, Higuchi, Korsmeyer–Peppas and Hixson–Crowell) applied on M and C sustained release formulations.

Sustained Release Formulation	Zero-Order	First-Order		Higuchi	Korsmeyer–Peppas		Hixson–Crowell
	R2	R2	K1	R2	R2	n	R2
MFb4c1tr after 2 h in pH 1.0	0.9902	0.9628	−0.1547	0.9945	0.9505	1.7155	0.9866
Mfb4c3tr after 2 h in pH 1.0	0.9873	0.8986	−0.0966	0.9889	0.9454	1.1917	0.9593
MFb4c1tr after 4 h in pH 4.5	0.9860	0.9789	−0.1797	0.9943	0.9481	2.5252	0.9921
Mfb4c3tr after 4 h in pH 4.5	0.9879	0.9643	−0.0862	0.9934	0.9609	1.3467	0.9885
Cfb4c6t	0.9929	0.8764	−0.0334	0.9680	0.9351	2.4742	0.9586
Cfb4c9t	0.9896	0.9338	−0.0434	0.9664	0.9226	1.3374	0.9835