Table 1.

Metabolites with significant changes after acute exercise and/or chronic training. Bold font indicates significance controlled by false discovery rate; provided p-values are uncorrected.

Metabolite	Metabolite Class	Acute Exercise Log2 Fold Change	Acute Exercise p-Value	Chronic Training Log2 Fold Change	Chronic Training p-Value
3-(4-hydroxyphenyl)-lactate	Amino Acid	1.92	4.03 × 10−4	−0.43	0.38
CoA-glutathione	Amino Acid	−1.26	8.07 × 10−4	−0.02	0.96
N-lactoylvaline *	Amino Acid	1.71	1.41 × 10−3	−0.08	0.82
3-methylhistidine	Amino Acid	1.24	2.19 × 10−3	−1.18	0.12
N-acetylvaline	Amino acid	0.12	0.87	−0.86	3.50 × 10−4
N-acetylleucine	Amino acid	−0.16	0.83	−0.75	2.21 × 10−3
beta-citrylglutamate	Amino acid	0.41	0.32	1.36	6.39 × 10−3
N-acetylphenylalanine	Amino acid	−0.35	0.62	−0.82	6.54 × 10−3
chenodeoxycholate	Lipid	0.92	3.06 × 10−3	−0.30	0.62
1-stearoyl-GPE (18:0)	Lipid	−0.18	0.63	−0.81	1.21 × 10−3
3-hydroxybutyrate (BHBA)	Lipid	0.28	0.71	−1.13	2.89 × 10−3
xanthosine	Nucleotide	2.01	5.41 × 10−4	−0.72	2.43 × 10−3
N1-methyl-2-pyridone-5-carboxamide	Cofactor & vitamin	1.37	2.02 × 10−3	−1.38	6.68 × 10−3
acetylphosphate	Energy	0.37	0.25	−1.31	3.53 × 10−3
fructose-1,6-bisphosphate	Carbohydrate	0.54	0.14	−1.49	3.62 × 10−3
sulfate	Xenobiotics	1.16	0.020	−1.75	5.97 × 10−3

* misidentified as 1-carboxyethylvaline in previous versions of the applied metabolomics platform.