Figure 1.

An overview of the most common structural hippocampus deviations in schizophrenia. Patients suffering from schizophrenia frequently develop a reduction of the general hippocampal volume, as well as a higher volume asymmetry between the left and right hippocampus. Furthermore, subfield-specific volume changes were especially described for the CA1- and CA2-region. Besides volume reductions, morphological abnormalities are known and include incomplete inversion patterns and inward deformations. Lastly, connectivity studies unraveled an impaired connection between the hippocampus of schizophrenic patients with further parts of the CNS.