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Release profile of VBL from 15% VBL-CS/HY NPs as a function of time and different pH values. Open squares: pH = 5; closed diamonds: pH = 7.4. In addition, the diffusion of free VBL at pH = 7.4 (closed circles) and at pH = 5.0 (open circles) are reported. See text for details. Results are presented as the means of six different experiments ± S.D.
