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Potential mechanisms underlying the antihyperglycemic actions exerted by targeted synthetic DMARDs (tsDMARDs). * Studies conducted in mice (baricitinib) and rats (tofacitinib). Abbreviations: CXCL9, C-X-C motif chemokine ligand 9; CXCL10, C-X-C motif chemokine ligand 10; DMARDs, disease-modifying antirheumatic drugs; IFN-γ, interferon-γ; IL, interleukin; SAA, serum amyloid A; TNF-α, tumor necrosis factor α.
