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In vivo delivery of mRNA-LNPs formulation. (a) Duration and expression pattern of LNPs-encapsulated Fluc mRNA in mice injected by i.v. and i.m. routes. BALB/c mice were injected with 10 µg of FLuc mRNA encapsulated by LNPs by the intramuscular (i.m.) and intravenous (i.v.) routes and representative IVIS images. (b) Representative Fluc expression in different organs for FLuc mRNA-LNP injected mice under IVIS imaging.
