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. 2022 May 18;11(10):2840. doi: 10.3390/jcm11102840

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Alternate Intraperitoneal Chemotherapy Treatment Modalities. Although HIPEC is the current standard-of-care intraperitoneal chemotherapy treatment option for PC from appendiceal and colorectal malignancies, other intraperitoneal chemotherapy treatment strategies are under investigation. NIPS (neoadjuvant intraperitoneal and systemic chemotherapy), PIPAC (pressurized intraperitoneal aerosol chemotherapy), HIPEC (hyperthermic intraperitoneal chemotherapy), NIPEC (normothermic intraperitoneal chemotherapy), EPIC (early postoperative intraperitoneal chemotherapy).