Table 2.
The difference in preoperative inflammatory and redox biomarkers between testicular GCT patients at lower and higher tumor stages.
| Laboratory Parameter | Stage I | Stages II + III | p-Value |
|---|---|---|---|
| Neutrophils (n × 109/L) | 4.55 (1.80–13.00) | 5.20 (2.70–12.22) | 0.077 |
| Lymphocytes (n × 109/L) | 1.90 (1.10–3.00) | 1.60 (0.40–3.32) | 0.183 |
| NLR | 2.28 (0.72–11.82) | 3.28 (1.65–16.00) | 0.005 * |
| dNLR | 1.71 (0.58–4.64) | 2.18 (1.18–5.77) | 0.031 * |
| Platelets (n × 109/L) | 234.00 (102.00–412.00) | 260.00 (148.00–562.00) | 0.177 |
| PLR | 123.68 (67.27–283.64) | 163.50 (51.61–640.00) | 0.008 * |
| SII (×109/L) | 533.33 (145.71–3687.27) | 824.26 (268.39–4096.00) | 0.001 * |
| SIRI (×109/L) | 1.06 (0.29–16.36) | 1.65 (0.58–6.42) | 0.001 * |
| Monocytes (n × 109/L) | 0.48 (0.10–1.30) | 0.50 (0.30–1.45) | 0.117 |
| LMR | 4.20 (0.85–13.00) | 3.20 (1.00–5.33) | 0.001 * |
| CRP (mg/L) | 0.80 (0.20–301.00) | 2.45 (0.20–197.50) | 0.008 * |
| AGR | 1.84 (1.23–2.78) | 1.62 (0.88–2.35) | 0.009 * |
| 8-OHdG (ng/mL) | 9.25 (5.07–49.50) | 8.51 (4.29–16.48) | 0.373 |
| Thiol groups (ng/mL) | 9.65 (4.98–218.86) | 10.16 (5.93–14.89) | 0.914 |
| MDA (ng/mL) | 94.01 (41.02–302.85) | 98.02 (55.34–372.06) | 0.208 |
NLR—neutrophil-to-lymphocytes ratio; dNLR—derived neutrophil-to-lymphocyte ratio (formula: neutrophil/(WBC-neutrophil)); PLR—platelet-to-lymphocyte ratio; SII—systemic immune-inflammation index (formula: neutrophil × platelet/lymphocyte); SIRI—systemic inflammation response index (formula: neutrophil × monocyte/lymphocyte); LMR—lymphocyte-to-monocyte ratio; CRP—C-reactive protein; AGR—serum albumin/(serum total protein-serum albumin); 8-OHdG—8-hydroxy-2′-deoxyguanosine; MDA—malondialdehyde; * p < 0.05.