Table 3.

Receiver operating characteristics (ROC) curve analysis for pre-orchiectomy inflammatory indices’ performance in predicting metastatic disease among patients diagnosed with testicular GCT.

Inflammatory Index	Cut-Off Point	AUC	p-Value	CI	Specificity (%)	Sensitivity (%)
NLR	2.685	0.691	0.05 *	0.573–0.809	67.79	70.37
dNLR	1.775	0.646	0.031 *	0.527–0.765	57.62	70.37
PLR	160.170	0.680	0.008 *	0.539–0.820	86.44	55.55
LMR	4.145	0.730	0.001 *	0.618–0.842	50.84	85.18
SII (×109/L)	683.21	0.714	0.001 *	0.549–0.836	66.10	70.37
SIRI (×109/L)	1.005	0.723	0.001 *	0.612–0.835	47.45	88.88
CRP (mg/L)	2.100	0.684	0.008 *	0.549–0.819	80.76	65.38
AGR	1.530	0.695	0.009 *	0.554–0.838	93.18	44.82

NLR—neutrophil-to-lymphocytes ratio; dNLR—derived neutrophil-to-lymphocyte ratio (formula: neutrophil/(WBC-neutrophil)); PLR—platelet-to-lymphocyte ratio; SII—systemic immune-inflammation index (formula: neutrophil × platelet/lymphocyte); SIRI—systemic inflammation response index (formula: neutrophil × monocyte/lymphocyte); LMR—lymphocyte-to-monocyte ratio; CRP—C-reactive protein; AGR—serum albumin/(serum total protein-serum albumin); AUC—area under the curve; CI—confidence interval; * p < 0.05.