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. 2022 May 4;12(5):744. doi: 10.3390/jpm12050744

Table 3.

Comparative analysis of biochemical parameters between HF patients without complications, with thrombosis and bleeding complications.

Study Groups Parameters Before 14 Days p-Value After 3–6 Months p-Value After 12–18 Month p-Value
Group 1 Hemoglobin, g/L 139.6 ± 18.2 129.5 ± 16.2 125.7 ± 20.0
Group 2-1 145.8 ± 21.7 0.32 * 129.0 ± 15.3 0.93 * 125.1 ± 18.4 0.95 *
Group 2-2 128.5 ± 21.2 0.052 * 111.1 ± 29.2 0.04 ** 117.6 ± 35.0 0.55 *
Group 1 Hematocrit, % 41.1 ± 6.72 38.2 ± 4.92 37.5 ± 5.46
Group 2-1 43.1 ± 6.95 0.39 * 37.0 ± 3.67 0.51 * 36.3 ± 6.14 0.58 *
Group 2-2 39.0 ± 6.61 0.30 * 32.8 ± 8.70 0.016 * 35.6 ± 10.3 0.63 *
Group 1 Lymphocytes, % 27.5 ± 9.25 26.2 ± 8.79 22.0 ± 6.44
Group 2-1 31.0 ± 8.78 0.19 ** 18.4 ± 6.34 0.015 * 29.8 ± 11.3 0.03 **
Group 2-2 21.8 ± 6.28 0.02 ** 24.8 ± 9.35 0.68 * 19.9 ± 11.3 0.27 **
Group 1 LDH, U/L 271.5 ± 137.0 273.5 ± 93.7 306.0 ± 156.1
Group 2-1 N/A 335.4 ± 133.3 0.24 ** 194.6 ± 42.7 0.02 **
Group 2-2 254.0 ± 171.9 0.38 ** 260.2 ± 139.0 0.78 * 377.4 ± 174.2 0.19 **
Group 1 AST, U/L 27.9 ± 21.4 19.6 ± 5.50 21.2 ± 8.08
Group 2-1 29.5 ± 10.6 0.11 ** 26.9 ± 19.0 0.42 ** 22.2 ± 8.44 0.77 *
Group 2-2 33.3 ± 27.0 0.43 ** 36.9 ± 37.5 0.02 ** 43.0 ± 70.3 0.63 **
Group 1 Total bilirubin, mg/dL 1.33 ± 1.56 0.70 ± 0.51 1.03 ± 1.51
Group 2-1 1.03 ± 0.73 0.74 ** 1.26 ± 0.58 0.01 ** 0.76 ± 0.80 0.55 **
Group 2-2 3.00 ± 5.09 0.40 ** 1.59 ± 2.76 0.77 ** 0.96 ± 0.71 0.42 **

Continuous variables are presented, mean ± SD. Student’s t-test p-value is labeled with one asterisk (*); Mann-Whitney U test’s p-value is labeled with double asterisks (**); the significant p value (p < 0.05) is labeled in bold; N/A, Not available. Group 1, without complications; Group 2-1, thrombosis; Group 2-2, bleeding; LDH, lactate dehydrogenase; AST, aspartate aminotransferase.