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. 2022 May 6;14(5):999. doi: 10.3390/pharmaceutics14050999

Table 1.

Clinical and demographic data of investigated cohorts.

Clinical and Demographic Data
Total N = 104
Treatment-resistant cohort N 42
age 18·79 ± 8.3 SD 3
Gender 74% male 4
Basal CGI 6 ± 0.99
Basal CGAS 30.02 ± 13.28
Control N 62
age 13.83 ± 3.8
Gender 92% male
Basal CGI 4.33 ± 0.80
Basal CGAS 44.32 ± 9
Medication
Treatment resistant Control
Antipsychotics 1 28 (67%) 29 (32%)
Antidepressants 2 20 (48%) 10 (11%)
Anxiolytics, anticonvulsants and others 21 (26%) 50 (56%)
No current medication 3 (7%) 0

1 Antipsychotic drugs used: risperidone (43%), aripiprazole (26%), olanzapine (14%), quetiapine (11%), paliperidone (6%). 2 Antidepressant drugs used: fluoxetine (39%), sertraline (26%), paroxetine (13%), fluvoxamine (3%), escitalopram (3%), duloxetine (9%), desvenlafaxine (6%). 3 The treatment-resistant cohort was relatively older than the control group (p = 0.001). 4 Gender distribution was not significantly different between cohorts (p = 0.10).