Table 3.

Details of the differentially abundant proteins identified between five NP and five PAS placenta tissues. We used 2D-DIGE and MALDI TOF/TOF to quantify and identify proteins, respectively. The theoretical pI/Mr, sequence coverage and score were determined by the MALDI TOP/TOF assay. The fold change and p-value were calculate by the 2D-DIGE assay. Positive fold change denoted a higher abundance in PAS samples. p-value was calculated based on a t-test.

Spot No.	SwissPort Entry Name	Protein Name	Theoretical pI/Mr	Sequence Coverage, MS%	Score	Fold Change	p-Value
1	A2KLM6	Immunoglobulin heavy chain variable region	5.25/11	77	68	−1.69	0.052
2	HSPA4	Heat shock 70 kDa protein 4	5.11/94.2	20	57	4.92	0.045
3	PRKAR2	cAMP-dependent protein kinase type II-alpha regulatory subunit	4.96/45.4	33	68	7.42	0.023
4	GSTP1	Glutathione S-transferase P	5.43/23.3	47	66	−1.50	0.054
5	MYNN	Myoneurin	5.72/10.6	79	69	−1.66	0.038
6	ZN211	Zinc finger protein 211	8.83/64.4	27	56	−1.65	0.041
7	UTS2	Urotensin-2 isoform a preproprotein	7/16	41	66	2.00	0.0052
8	ZN157	Zinc finger protein 157	8.83/58.2	29	62	1.98	0.025
9	ACTB	Actin, cytoplasmic 1	5.29/41.7	25	58	5.36	0.021
10	CSH	Chorionic somatomammotropin hormone	5.34/25	57	147	−1.63	0.028
11	IQEC1	IQ motif and SEC7 domain-containing protein 1	6.49/108	17	58	2.54	0.053
12	CLIC1	Chloride intracellular channel protein 1	5.09/26.9	51	140	1.54	0.037
13	PMFBP	Polyamine-modulated factor 1-binding protein 1	5.94/118	22	59	1.91	0.010
14	DDX4	Probable ATP-dependent RNA helicase DDX4	5.62/79.2	20	57	−1.51	0.014
15	PLXB2	Plexin-B2	5.85/204	15	58	−1.63	0.044
16	D3DT17	hCG2038441	9.28/16.3	65	67	1.59	0.035
17	B7ZC06	Golgi autoantigen, golgin subfamily a, 2	6.05/53.3	20	67	1.62	0.0032
18	AMBP	Protein AMBP	5.95/38.9	38	56	−1.67	0.025
19	ANXA2	Annexin A2	7.57/38.5	28	86	−1.56	0.0060