Figure 5.

Biodistribution of fluorescent dye (Cy7) after intra-arterial injection of capsules labeled with BSA-Cy7 and its free solution (A–D). Time dependence of integrated total radiant efficiency by all dissected organs (A). Kinetics of the biodistribution of Cy7 (B). Time dependence of Cy7 content in the kidneys expressed as a percentage of injected dose after administration of capsules labeled with BSA-Cy7 (C) and free BSA-Cy7 conjugate (D). Fluorescent microscopy of the kidney’s cryosections after 10 × 10${}^6$ capsules’ injection (E). The detection channel was adjusted to RITC fluorescence. The scale bar is 50 $\mathsf{\mu }$m.