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. 2022 Apr 22;14(5):917. doi: 10.3390/pharmaceutics14050917

Table 1.

Clinical organic and inorganic nanoparticles designed for cancer imaging or therapy.

NP Type Drugs Loaded Clinical Stage Reference
Organic NPs Liposome Irinotecan, Doxorubicin, mRNAs FDA-approved [22]
Polymeric Nanoparticles Paclitaxel, Gemcytabine, Doxorubicin, Platinum FDA-approved [23]
Dendrimer Camptothecin, Doxorubicin Preclinical [24,25]
Metallic and inorganic NPs Mesoporous Silica Nanoparticle (MSN) Gemcitabine, Paclitaxel or Irinotecan Preclinical [25,26]
Carbon Dots (CDs) Gemcitabine or Cyanine 7 Preclinical [25,27,28]
Graphene Quantum Dots (CQDs) Gemcitabine Preclinical [29]
Gold Nanoparticles (AuNPs) Gemcitabine and miR-21 inhibitor or Cetuximab Clinical Phase I/II [29,30,31,32]
Iron Oxide Nanoparticles (IONPs) Gemcitabine or Doxorubicin or Imiquimod FDA-approved [33,34,35,36,37]