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. 2022 Apr 30;12(5):732. doi: 10.3390/jpm12050732

Table 1.

Baseline characteristics in patients with and without AF recurrence.

Total
(N = 120)
Non-Recurrence
(N = 89)
Recurrence
(N = 31)
p
Baseline demographics
 Male 84 (70.0%) 66 (74.2%) 18 (58.1%) 0.092
 Age (y) 61.9 ± 9.3 62.3 ± 9.0 61.0 ± 10.2 0.504
 Age ≥ 65 years 52 (43.3%) 41 (46.1%) 11 (35.5%) 0.306
 Body mass index 25.98 ± 3.76 25.9 ± 3.6 26.3 ± 4.2 0.529
 Left ventricular ejection fraction (%) 55.9 ± 8.5 56 ± 8.9 55.4 ± 7.5 0.746
 Left atrium diameter (cm) 4.38 ± 0.71 4.4 ± 0.7 4.7 ± 0.8 0.035
 Left atrium enlargement ≥ 45 mm 53 (46.1%) 36 (42.4%) 17 (56.7%) 0.176
 NYHA functional class 0.975 ± 0.399 1.0± 0.4 1.0± 0.4 0.355
AF characteristics
 AF duration (months) 48.0 ± 78.9 44.9 ± 70.7 57.7 ± 101 0.546
 AF duration ≥3 years 41 (37.3%) 30 (36.1%) 11 (40.7%) 0.668
 Paroxysmal AF 87 (72.5%) 72 (80.9%) 15 (48.4%) 0.001
 Persistent AF 33 (27.5%) 17 (19.1%) 16 (51.6%) 0.001
 Prior electrical cardioversion 9 (7.5%) 4 (4.5%) 5 (16.1%) 0.049
Comorbidities
 Left ventricular hypertrophy 100 (86.2%) 74 (86%) 26 (86.7%) 1.000
 Valvular heart disease 67 (57.8%) 47 (54.7%) 20 (66.7%) 0.251
 Obstructive sleep apnea 4 (3.3%) 3 (3.4%) 1 (3.2%) 1.000
 COPD 0 (0%) 0 (0%) 0 (0%) -
 Hypertension 66 (55%) 47 (52.8%) 19 (61.3%) 0.414
 Hyperlipidemia 48 (40%) 34 (38.2%) 14 (45.2%) 0.496
 Diabetes mellitus 15 (12.5%) 11 (12.4%) 4 (12.9%) 1.000
 Chronic kidney disease 11 (9.2%) 9 (10.1%) 2 (6.5%) 0.727
 Stroke or TIA 17 (14.2%) 14 (15.7%) 3 (9.7%) 0.555
 CAD 29 (24%) 25 (28.1%) 4 (12.9%) 0.089
 CABG 1 (0.8%) 1 (1.1%) 0 (0%) 1.000
 CHA2DS2-VASc score 1.97 ± 1.58 2± 1.6 2 ± 1.6 0.997
Medications
 Anti-platelet agents 41 (34.2%) 29 (32.6%) 12 (38.7%) 0.536
 CCB 32 (26.7%) 20 (22.5%) 12 (38.7%) 0.078
 Beta blockers 53 (44.2%) 39 (43.8%) 14 (45.2%) 0.897
 ACEi/ARB 42 (35%) 30 (33.7%) 12 (38.7%) 0.615
 OAC 79 (65.8%) 59 (66.3%) 20 (64.5%) 0.858
 AADs 101 (84.2%) 78 (87.6%) 23 (74.2%) 0.091
 Class I AADs 56 (46.7%) 46 (51.7%) 10 (32.3%) 0.094
 Class III AADs 51 (42.5%) 36 (40.4%) 15 (48.4%) 0.528

Abbreviations: AF, atrial fibrillation; NYHA, New York Heart Association; COPD, chronic obstructive pulmonary disease; TIA, transient ischemic attack; CAD, coronary artery disease; CABG, coronary artery bypass surgery; CCB, calcium channel blocker; ACEi, angiotensin-converting enzyme inhibitor; ARB, angiotensin II receptor blocker; OAC, oral anticoagulant; AADs, anti-arrhythmic drugs.